The longtime Venice, California, studio of the interdisciplinary 20th century designers, Ray and Charles Eames, was a deceptive piece of ho-hum commercial architecture. It belied the world-changing design taking place inside. The Eameses helped shape 20th century design, culture, and innovation—from more comfortable molded plywood leg splits (for injured WWII soldiers) to imagination-sparking children’s toys and games to their sleek, streamlined furniture that continues to be produced by...

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