2025 U.S Summer Internship Program: High-plex Spatial Transcriptomics Biomarker Assay Development fo

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Job Description

Takeda has been translating science into breakthrough medicines for 240 years. Every step of the way, our teams have worked together to tackle some of the most challenging problems in drug discovery and development. Today, we're a driving force behind innovative therapies that make a lasting difference to millions of patients around the world.

In R&D, all of our history and potential comes together in an environment that welcomes diversity of thought and amplifies every voice. Working closely with colleagues, you'll play a key role in bringing our rich pipeline of products forward to help patients. Come join a team that's earned trust for more than two centuries, and find out how advancing transformative therapies at Takeda will shape your bright future.

Autoimmune diseases are a group of diverse diseases with a common cause in which the immune system responds to self-antigens, leading to damage or dysfunction of tissues. Biomarkers are measurable substances in the body associated with the intensity of a disease or other physiological states. They can be used in the diagnosis, prognosis, and treatment of different diseases. The summer internship project aims to:

• Use clinical samples of autoimmune diseases with respective control group samples

• Screen for miRNA, mRNA, and Protein biomarkers using high-plex multi-omics spatial transcriptomics platforms to identify disease-specific or common autoimmune biomarkers

• Use the NanoString nCounter platform to identify miRNA biomarker candidates in clinical serum samples of autoimmune disease patients. This platform uses a unique barcode system and can directly detect up to 799 target genes in a single sample without amplification. FFPE or freshly frozen tissue samples will be used for the spatial transcriptomic analysis. By unraveling the transcriptomic biomarkers at miRNA, RNA, and protein levels, the project aims to understand the disease-specific biomarkers of autoimmune diseases at the transcription and translational levels.

• The intern will be involved in

• Sample processing, reagent preparation, reaction setup, instrumentation learning, and data analysis for the nCounter and spatial transcriptomic platforms

Internship Development Opportunities:

• After the internship, the intern is expected to be proficient in the high-plex multi-omic assay workflow, understand hypothesis-driven experiment design, and be able to share findings at Takeda's inter departmental meetings.

Job Requirements:

• This position will be Fully Onsite and require 4+ days in the Cambridge, MA office per week.

• Must be pursuing a Master's or Doctoral Degree with a background in molecular biology, bioinformatics, and biochemistry being preferred

• Basic understanding of computer skills including MS Office (PowerPoint, Words, Excel)

• Internet skills including use of e-mails, group messaging and information gathering

• Highly reliable and a strong team player

• Flexible with an attention to detail

• Strong verbal and written communication skills

Internship Eligibility

• Must be authorized to work in the U.S. on a permanent basis without requiring sponsorship

• Must be currently enrolled in a degree program graduating December 2025 or later

• The internship program is 10-12 weeks depending on the two start dates (June 2nd- August 22nd) or (June 16th - August 29th)

• The intern must be able to commit to one of these time frames

• Able to work full time 40 hours a week during internship dates

• Takeda does not provide a housing stipend or relocation support for the U.S Summer Internship Program

Program Highlights:

• Hands-on experience with real projects and responsibilities

• Dedicated mentorship program pairing interns with experienced professionals

• Networking opportunities with industry professionals and fellow interns

• Internship events focused on professional and skills development

• Exposure to multiple business areas or departments within a Pharmaceutical Organization

Applications will be accepted between January 6th and January 31st

Takeda Compensation and Benefits Summary

We understand compensation may be an important factor as you consider an internship opportunity. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

USA - MA - Cambridge - Binney St

U.S. Hourly Wage Range:

$21.00 - $46.00

The estimated hourly range reflects an anticipated range for this position. The actual hourly wage offered will depend on the candidate's school year/level to be entered following completion of internship. The actual hourly wage offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. internship benefits vary by location and may include:

• Paid sick time

• Civic Duty paid time off

• Participation at company volunteer events

• Participation at company sponsored special events

• Access to on-site fitness center (where available)

• Commuter Benefit: To offset your work-commute expenses, Takeda provides U.S. employees with a fixed monthly subsidy to be used for either public transportation (transit) or parking.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

USA - MA - Cambridge - Binney St

Worker Type

Employee

Worker Sub-Type

Paid Intern (Fixed Term) (Trainee)

Time Type

Full time

Job Exempt

No